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Description for Protein HSF1

heat shock transcription factor 1
50 total interacting proteins; 27 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The product of this gene is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and/or associated with multichaperone complexes, is a major repressor of this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • HSF: heat shock factor
  • LZ: Leucine Zipper

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K09414
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Heat-shock factor 1; HSTF 1
    Approved Symbol:
    HSF1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 21
    Human (de-) phosphorylation sites: 21; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 00778 Entrez Gene ID: 3297 OMIM ID: 140580 Swissprot Accession: Q00613