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Gene Ontology Information for protein APEX1

Biological Process?

anti-apoptosis (Total: 245, Platelet: 105) (Children)
base-excision repair (Total: 34, Platelet: 4) (Children)
biological regulation (Total: 7303, Platelet: 2182) (Children)
biological_process (Total: 14352, Platelet: 4135) (Children)
cell redox homeostasis (Total: 65, Platelet: 39) (Children)
cellular homeostasis (Total: 511, Platelet: 197) (Children)
cellular macromolecule metabolic process (Total: 5820, Platelet: 1619) (Children)
cellular metabolic process (Total: 7674, Platelet: 2355) (Children)
cellular nitrogen compound metabolic process (Total: 4830, Platelet: 1241) (Children)
cellular process (Total: 11864, Platelet: 3614) (Children)
cellular response to stimulus (Total: 1418, Platelet: 490) (Children)
cellular response to stress (Total: 818, Platelet: 269) (Children)
DNA metabolic process (Total: 647, Platelet: 160) (Children)
DNA repair (Total: 338, Platelet: 65) (Children)
gene expression (Total: 3814, Platelet: 856) (Children)
homeostatic process (Total: 897, Platelet: 322) (Children)
macromolecule metabolic process (Total: 6391, Platelet: 1787) (Children)
metabolic process (Total: 8630, Platelet: 2635) (Children)
mRNA metabolic process (Total: 443, Platelet: 132) (Children)
negative regulation of apoptosis (Total: 427, Platelet: 170) (Children)
negative regulation of biological process (Total: 2258, Platelet: 752) (Children)
negative regulation of cell death (Total: 439, Platelet: 175) (Children)
negative regulation of cellular process (Total: 2091, Platelet: 689) (Children)
negative regulation of programmed cell death (Total: 432, Platelet: 172) (Children)
nitrogen compound metabolic process (Total: 4932, Platelet: 1276) (Children)
nucleic acid metabolic process (Total: 3838, Platelet: 807) (Children)
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process (Total: 4430, Platelet: 1064) (Children)
positive regulation of anti-apoptosis (Total: 35, Platelet: 16) (Children)
positive regulation of biological process (Total: 2456, Platelet: 839) (Children)
positive regulation of cellular metabolic process (Total: 1109, Platelet: 339) (Children)
positive regulation of cellular process (Total: 2218, Platelet: 743) (Children)
positive regulation of DNA metabolic process (Total: 69, Platelet: 23) (Children)
positive regulation of DNA repair (Total: 20, Platelet: 3) (Children)
positive regulation of macromolecule metabolic process (Total: 1073, Platelet: 316) (Children)
positive regulation of metabolic process (Total: 1159, Platelet: 355) (Children)
positive regulation of nitrogen compound metabolic process (Total: 790, Platelet: 187) (Children)
positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process (Total: 767, Platelet: 172) (Children)
positive regulation of response to stimulus (Total: 402, Platelet: 165) (Children)
posttranscriptional regulation of gene expression (Total: 254, Platelet: 124) (Children)
primary metabolic process (Total: 7785, Platelet: 2334) (Children)
regulation of anti-apoptosis (Total: 42, Platelet: 21) (Children)
regulation of apoptosis (Total: 971, Platelet: 391) (Children)
regulation of biological process (Total: 6792, Platelet: 2001) (Children)
regulation of biological quality (Total: 2091, Platelet: 821) (Children)
regulation of cell death (Total: 986, Platelet: 397) (Children)
regulation of cellular metabolic process (Total: 3844, Platelet: 947) (Children)
regulation of cellular process (Total: 6378, Platelet: 1857) (Children)
regulation of cellular response to stress (Total: 151, Platelet: 56) (Children)
regulation of DNA metabolic process (Total: 144, Platelet: 41) (Children)
regulation of DNA repair (Total: 29, Platelet: 7) (Children)
regulation of gene expression (Total: 3006, Platelet: 610) (Children)
regulation of macromolecule metabolic process (Total: 3469, Platelet: 808) (Children)
regulation of metabolic process (Total: 4150, Platelet: 1057) (Children)
regulation of mRNA stability (Total: 28, Platelet: 16) (Children)
regulation of nitrogen compound metabolic process (Total: 3160, Platelet: 654) (Children)
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process (Total: 3088, Platelet: 601) (Children)
regulation of primary metabolic process (Total: 3643, Platelet: 875) (Children)
regulation of programmed cell death (Total: 978, Platelet: 395) (Children)
regulation of response to stimulus (Total: 729, Platelet: 311) (Children)
regulation of response to stress (Total: 428, Platelet: 193) (Children)
regulation of RNA metabolic process (Total: 1981, Platelet: 359) (Children)
regulation of RNA stability (Total: 29, Platelet: 16) (Children)
response to DNA damage stimulus (Total: 494, Platelet: 139) (Children)
response to stimulus (Total: 4334, Platelet: 1386) (Children)
response to stress (Total: 2244, Platelet: 861) (Children)
RNA metabolic process (Total: 2735, Platelet: 551) (Children)


Molecular Function?

3'-5' exonuclease activity (Total: 28, Platelet:2) (Children)
binding (Total: 12782, Platelet: 3830) (Children)
carbon-oxygen lyase activity (Total: 54, Platelet:22) (Children)
catalytic activity (Total: 5218, Platelet: 1872) (Children)
cation binding (Total: 3785, Platelet: 954) (Children)
chromatin binding (Total: 192, Platelet:33) (Children)
chromatin DNA binding (Total: 12, Platelet:1) (Children)
damaged DNA binding (Total: 51, Platelet:10) (Children)
deoxyribonuclease activity (Total: 39, Platelet:4) (Children)
DNA binding (Total: 2247, Platelet: 338) (Children)
DNA N-glycosylase activity (Total: 13, Platelet: ) (Children)
DNA-(apurinic or apyrimidinic site) lyase activity (Total: 11, Platelet:1) (Children)
endodeoxyribonuclease activity (Total: 28, Platelet:1) (Children)
endonuclease activity (Total: 100, Platelet:6) (Children)
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters (Total: 37, Platelet:1) (Children)
endoribonuclease activity (Total: 46, Platelet:1) (Children)
endoribonuclease activity, producing 5'-phosphomonoesters (Total: 25, Platelet: ) (Children)
exonuclease activity (Total: 59, Platelet:10) (Children)
hydrolase activity (Total: 2290, Platelet: 808) (Children)
hydrolase activity, acting on ester bonds (Total: 705, Platelet: 204) (Children)
hydrolase activity, acting on glycosyl bonds (Total: 117, Platelet:31) (Children)
hydrolase activity, hydrolyzing N-glycosyl compounds (Total: 21, Platelet:5) (Children)
ion binding (Total: 3795, Platelet: 958) (Children)
lyase activity (Total: 160, Platelet:71) (Children)
metal ion binding (Total: 3741, Platelet: 940) (Children)
molecular_function (Total: 15594, Platelet: 4389) (Children)
nuclease activity (Total: 164, Platelet:21) (Children)
nucleic acid binding (Total: 3182, Platelet: 610) (Children)
oxidoreductase activity (Total: 686, Platelet: 289) (Children)
phosphodiesterase I activity (Total: 4, Platelet:1) (Children)
phosphoric diester hydrolase activity (Total: 87, Platelet:27) (Children)
phosphoric ester hydrolase activity (Total: 343, Platelet:120) (Children)
protein binding (Total: 8959, Platelet: 2987) (Children)
protein binding transcription factor activity (Total: 371, Platelet:88) (Children)
ribonuclease activity (Total: 67, Platelet:3) (Children)
ribonuclease H activity (Total: 6, Platelet: ) (Children)
site-specific endodeoxyribonuclease activity, specific for altered base (Total: 2, Platelet: ) (Children)
structure-specific DNA binding (Total: 194, Platelet:37) (Children)
transcription coactivator activity (Total: 217, Platelet:49) (Children)
transcription cofactor activity (Total: 371, Platelet:88) (Children)
transcription corepressor activity (Total: 151, Platelet:34) (Children)
transcription factor binding transcription factor activity (Total: 371, Platelet:88) (Children)
uracil DNA N-glycosylase activity (Total: 4, Platelet: ) (Children)


Cellular Component?

cell (Total: 14910, Platelet: 4246) (Children)
cell part (Total: 14909, Platelet: 4246) (Children)
cellular_component (Total: 16194, Platelet: 4465) (Children)
centrosome (Total: 207, Platelet: 71) (Children)
cytoplasm (Total: 7967, Platelet: 3091) (Children)
cytoplasmic part (Total: 5701, Platelet: 2428) (Children)
cytoskeletal part (Total: 1016, Platelet: 354) (Children)
cytoskeleton (Total: 1480, Platelet: 552) (Children)
endoplasmic reticulum (Total: 1059, Platelet: 449) (Children)
intracellular (Total: 11408, Platelet: 3621) (Children)
intracellular membrane-bounded organelle (Total: 8536, Platelet: 2625) (Children)
intracellular non-membrane-bounded organelle (Total: 3037, Platelet: 992) (Children)
intracellular organelle (Total: 9480, Platelet: 2972) (Children)
intracellular organelle lumen (Total: 2445, Platelet: 739) (Children)
intracellular organelle part (Total: 5569, Platelet: 1945) (Children)
intracellular part (Total: 11122, Platelet: 3557) (Children)
macromolecular complex (Total: 3356, Platelet: 1229) (Children)
membrane-bounded organelle (Total: 8543, Platelet: 2629) (Children)
membrane-enclosed lumen (Total: 2523, Platelet: 780) (Children)
microtubule cytoskeleton (Total: 647, Platelet: 222) (Children)
microtubule organizing center (Total: 315, Platelet: 101) (Children)
mitochondrion (Total: 1324, Platelet: 572) (Children)
non-membrane-bounded organelle (Total: 3037, Platelet: 992) (Children)
nuclear body (Total: 205, Platelet: 46) (Children)
nuclear lumen (Total: 2057, Platelet: 539) (Children)
nuclear part (Total: 2434, Platelet: 673) (Children)
nuclear speck (Total: 123, Platelet: 31) (Children)
nucleolus (Total: 1096, Platelet: 321) (Children)
nucleoplasm (Total: 1227, Platelet: 284) (Children)
nucleoplasm part (Total: 673, Platelet: 126) (Children)
nucleus (Total: 5323, Platelet: 1311) (Children)
organelle (Total: 9495, Platelet: 2974) (Children)
organelle lumen (Total: 2487, Platelet: 770) (Children)
organelle part (Total: 5639, Platelet: 1973) (Children)
perinuclear region of cytoplasm (Total: 346, Platelet: 158) (Children)
ribonucleoprotein complex (Total: 501, Platelet: 171) (Children)
ribosome (Total: 194, Platelet: 79) (Children)