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Gene Ontology Information for protein APAF1

Biological Process?

activation of caspase activity (Total: 70, Platelet: 32) (Children)
activation of caspase activity by cytochrome c (Total: 10, Platelet: 7) (Children)
anatomical structure development (Total: 3019, Platelet: 932) (Children)
anatomical structure formation involved in morphogenesis (Total: 514, Platelet: 154) (Children)
anatomical structure morphogenesis (Total: 1488, Platelet: 461) (Children)
apoptosis (Total: 1236, Platelet: 480) (Children)
apoptotic nuclear change (Total: 32, Platelet: 13) (Children)
biological regulation (Total: 7303, Platelet: 2182) (Children)
biological_process (Total: 14352, Platelet: 4135) (Children)
brain development (Total: 336, Platelet: 88) (Children)
catabolic process (Total: 1361, Platelet: 579) (Children)
cell death (Total: 1357, Platelet: 533) (Children)
cellular catabolic process (Total: 1083, Platelet: 471) (Children)
cellular component disassembly (Total: 312, Platelet: 145) (Children)
cellular component disassembly at cellular level (Total: 309, Platelet: 143) (Children)
cellular component disassembly involved in apoptosis (Total: 73, Platelet: 36) (Children)
cellular component organization (Total: 3404, Platelet: 1223) (Children)
cellular component organization at cellular level (Total: 2282, Platelet: 831) (Children)
cellular component organization or biogenesis (Total: 3514, Platelet: 1239) (Children)
cellular component organization or biogenesis at cellular level (Total: 2376, Platelet: 845) (Children)
cellular macromolecule catabolic process (Total: 501, Platelet: 210) (Children)
cellular macromolecule metabolic process (Total: 5820, Platelet: 1619) (Children)
cellular metabolic process (Total: 7674, Platelet: 2355) (Children)
cellular nitrogen compound metabolic process (Total: 4830, Platelet: 1241) (Children)
cellular process (Total: 11864, Platelet: 3614) (Children)
central nervous system development (Total: 485, Platelet: 129) (Children)
chordate embryonic development (Total: 382, Platelet: 91) (Children)
death (Total: 1360, Platelet: 535) (Children)
defense response (Total: 812, Platelet: 288) (Children)
developmental process (Total: 3603, Platelet: 1072) (Children)
DNA catabolic process (Total: 69, Platelet: 22) (Children)
DNA catabolic process, endonucleolytic (Total: 26, Platelet: 12) (Children)
DNA fragmentation involved in apoptotic nuclear change (Total: 26, Platelet: 12) (Children)
DNA metabolic process (Total: 647, Platelet: 160) (Children)
embryo development (Total: 669, Platelet: 147) (Children)
embryo development ending in birth or egg hatching (Total: 388, Platelet: 93) (Children)
embryonic epithelial tube formation (Total: 54, Platelet: 9) (Children)
embryonic morphogenesis (Total: 358, Platelet: 63) (Children)
epithelial tube formation (Total: 55, Platelet: 9) (Children)
epithelial tube morphogenesis (Total: 153, Platelet: 33) (Children)
epithelium development (Total: 398, Platelet: 101) (Children)
forebrain development (Total: 184, Platelet: 50) (Children)
induction of apoptosis (Total: 363, Platelet: 148) (Children)
induction of apoptosis by intracellular signals (Total: 81, Platelet: 42) (Children)
induction of programmed cell death (Total: 364, Platelet: 148) (Children)
macromolecule catabolic process (Total: 628, Platelet: 266) (Children)
macromolecule metabolic process (Total: 6391, Platelet: 1787) (Children)
metabolic process (Total: 8630, Platelet: 2635) (Children)
morphogenesis of an epithelium (Total: 242, Platelet: 58) (Children)
morphogenesis of embryonic epithelium (Total: 81, Platelet: 14) (Children)
multicellular organismal development (Total: 3297, Platelet: 972) (Children)
multicellular organismal process (Total: 5009, Platelet: 1402) (Children)
nervous system development (Total: 1368, Platelet: 420) (Children)
neural tube closure (Total: 36, Platelet: 6) (Children)
neural tube development (Total: 82, Platelet: 12) (Children)
neural tube formation (Total: 47, Platelet: 8) (Children)
neuron apoptosis (Total: 104, Platelet: 42) (Children)
neuron death (Total: 106, Platelet: 44) (Children)
nitrogen compound metabolic process (Total: 4932, Platelet: 1276) (Children)
nucleic acid metabolic process (Total: 3838, Platelet: 807) (Children)
nucleic acid phosphodiester bond hydrolysis (Total: 48, Platelet: 15) (Children)
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process (Total: 4430, Platelet: 1064) (Children)
organ development (Total: 1848, Platelet: 544) (Children)
positive regulation of apoptosis (Total: 492, Platelet: 189) (Children)
positive regulation of biological process (Total: 2456, Platelet: 839) (Children)
positive regulation of caspase activity (Total: 81, Platelet: 37) (Children)
positive regulation of catalytic activity (Total: 623, Platelet: 268) (Children)
positive regulation of cell death (Total: 500, Platelet: 192) (Children)
positive regulation of cellular process (Total: 2218, Platelet: 743) (Children)
positive regulation of hydrolase activity (Total: 254, Platelet: 111) (Children)
positive regulation of molecular function (Total: 717, Platelet: 305) (Children)
positive regulation of peptidase activity (Total: 81, Platelet: 37) (Children)
positive regulation of programmed cell death (Total: 495, Platelet: 191) (Children)
primary metabolic process (Total: 7785, Platelet: 2334) (Children)
primary neural tube formation (Total: 39, Platelet: 7) (Children)
programmed cell death (Total: 1243, Platelet: 484) (Children)
regulation of apoptosis (Total: 971, Platelet: 391) (Children)
regulation of biological process (Total: 6792, Platelet: 2001) (Children)
regulation of caspase activity (Total: 109, Platelet: 49) (Children)
regulation of catalytic activity (Total: 989, Platelet: 393) (Children)
regulation of cell death (Total: 986, Platelet: 397) (Children)
regulation of cellular process (Total: 6378, Platelet: 1857) (Children)
regulation of endopeptidase activity (Total: 117, Platelet: 54) (Children)
regulation of hydrolase activity (Total: 433, Platelet: 191) (Children)
regulation of metabolic process (Total: 4150, Platelet: 1057) (Children)
regulation of molecular function (Total: 1198, Platelet: 458) (Children)
regulation of peptidase activity (Total: 122, Platelet: 59) (Children)
regulation of programmed cell death (Total: 978, Platelet: 395) (Children)
response to stimulus (Total: 4334, Platelet: 1386) (Children)
response to stress (Total: 2244, Platelet: 861) (Children)
system development (Total: 2744, Platelet: 845) (Children)
tissue development (Total: 877, Platelet: 235) (Children)
tissue morphogenesis (Total: 313, Platelet: 80) (Children)
tube closure (Total: 37, Platelet: 6) (Children)
tube development (Total: 284, Platelet: 69) (Children)
tube formation (Total: 60, Platelet: 9) (Children)
tube morphogenesis (Total: 190, Platelet: 41) (Children)


Molecular Function?

adenyl nucleotide binding (Total: 1581, Platelet: 672) (Children)
adenyl ribonucleotide binding (Total: 1502, Platelet: 636) (Children)
apoptotic protease activator activity (Total: 19, Platelet:7) (Children)
ATP binding (Total: 1479, Platelet: 627) (Children)
binding (Total: 12782, Platelet: 3830) (Children)
caspase activator activity (Total: 17, Platelet:5) (Children)
caspase regulator activity (Total: 33, Platelet:14) (Children)
enzyme activator activity (Total: 365, Platelet:147) (Children)
enzyme regulator activity (Total: 891, Platelet: 358) (Children)
identical protein binding (Total: 707, Platelet: 273) (Children)
molecular_function (Total: 15594, Platelet: 4389) (Children)
nucleoside binding (Total: 1626, Platelet: 693) (Children)
nucleotide binding (Total: 2297, Platelet: 996) (Children)
peptidase activator activity (Total: 26, Platelet:11) (Children)
peptidase regulator activity (Total: 183, Platelet:85) (Children)
protein binding (Total: 8959, Platelet: 2987) (Children)
purine nucleoside binding (Total: 1616, Platelet: 691) (Children)
purine nucleotide binding (Total: 1931, Platelet: 865) (Children)
purine ribonucleotide binding (Total: 1850, Platelet: 827) (Children)
ribonucleotide binding (Total: 1850, Platelet: 827) (Children)


Cellular Component?

cell (Total: 14910, Platelet: 4246) (Children)
cell fraction (Total: 1085, Platelet: 448) (Children)
cell part (Total: 14909, Platelet: 4246) (Children)
cellular_component (Total: 16194, Platelet: 4465) (Children)
cytoplasm (Total: 7967, Platelet: 3091) (Children)
cytoplasmic part (Total: 5701, Platelet: 2428) (Children)
cytosol (Total: 1890, Platelet: 968) (Children)
Golgi apparatus (Total: 957, Platelet: 416) (Children)
intracellular (Total: 11408, Platelet: 3621) (Children)
intracellular membrane-bounded organelle (Total: 8536, Platelet: 2625) (Children)
intracellular non-membrane-bounded organelle (Total: 3037, Platelet: 992) (Children)
intracellular organelle (Total: 9480, Platelet: 2972) (Children)
intracellular organelle lumen (Total: 2445, Platelet: 739) (Children)
intracellular organelle part (Total: 5569, Platelet: 1945) (Children)
intracellular part (Total: 11122, Platelet: 3557) (Children)
membrane-bounded organelle (Total: 8543, Platelet: 2629) (Children)
membrane-enclosed lumen (Total: 2523, Platelet: 780) (Children)
non-membrane-bounded organelle (Total: 3037, Platelet: 992) (Children)
nuclear lumen (Total: 2057, Platelet: 539) (Children)
nuclear part (Total: 2434, Platelet: 673) (Children)
nucleolus (Total: 1096, Platelet: 321) (Children)
nucleus (Total: 5323, Platelet: 1311) (Children)
organelle (Total: 9495, Platelet: 2974) (Children)
organelle lumen (Total: 2487, Platelet: 770) (Children)
organelle part (Total: 5639, Platelet: 1973) (Children)
soluble fraction (Total: 323, Platelet: 155) (Children)