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Description for Protein HIVEP1

human immunodeficiency virus type I enhancer binding protein 1
9 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Members of the ZAS family, such as ZAS1 (HIVEP1), are large proteins that contain a ZAS domain, a modular protein structure consisting of a pair of C2H2 zinc fingers with an acidic-rich region and a serine/threonine-rich sequence. These proteins bind specific DNA sequences, including the kappa-B motif (GGGACTTTCC), in the promoters and enhancer regions of several genes and viruses, including human immunodeficiency virus (HIV). ZAS genes span more than 150 kb and contain at least 10 exons, one of which is longer than 5.5 kb (Allen and Wu, 2004).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • ZNFC2: zinc finger
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K09239
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Major histocompatibility complex binding protein 1; Positive regulatory domain II binding factor 1; Human immunodeficiency virus type 1 enchancer binding protein 1; ZNF40; HIV EP1; MBP 1; PRDII BF1
    Approved Symbol:
    HIVEP1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 23
    Human (de-) phosphorylation sites: 23; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01925 Entrez Gene ID: 3096 OMIM ID: 194540 Swissprot Accession: P15822;