Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein NT5C

5', 3'-nucleotidase, cytosolic
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 3/0)
(platelet: 2; secretome: 1)
Summary:
Pyrimidine 5-prime nucleotidase (P5N; EC 3.1.3.5), also called uridine 5-prime monophosphate hydrolase (UMPH), catalyzes the dephosphorylation of the pyrimidine 5-prime monophosphates UMP and CMP to the corresponding nucleosides. There are 2 isozymes of pyrimidine 5-prime nucleotidase in red blood cells, referred to as type I (UMPH1; MIM 606224) and type II (UMPH2).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
3.1.3.5
KEGG - Orthology:
K01081
KEGG - Pathway(s):
hsa00230; hsa00240; hsa00760; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
DNT; cdN; DNT1; P5N2; PN-I; PN-II; UMPH2; dNT-1; 5`(3`)-deoxyribonucleotidase; Uridine 5`-monophosphate phosphohydrolase 2; 5` Nucleotidase, deoxy (pyrimidine), cytosolic type C; Deoxyribonucleotidase, cytosolic 1; Deoxy-5`-nucleotidase 1; Cytosolic 5`,3`-pyrimidine nucleotidase; Pyrimidine 5-prime nucleotidase 2; Uridine 5-prime monophosphate hydrolase 2
Approved Symbol:
NT5C
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 1
Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 11833 Entrez Gene ID: 30833 OMIM ID: 191720 Swissprot Accession: Q8TCD5;