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Description for Protein NCKAP1L

NCK-associated protein 1-like
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 3/0)
(membrane: 1; platelet: 2)
Summary:
This gene encodes a member of the HEM family of tissue-specific transmembrane proteins which are highly conserved from invertebrates through mammals. This gene is only expressed in hematopoietic cells. The encoded protein is a part of the Scar/WAVE complex which plays an important role in regulating cell shape in both metazoans and plants. Alternatively spliced transcript variants encoding different isoforms have been found. (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K05750
KEGG - Pathway(s):
hsa04810
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Membrane-associated protein HEM-1; Hematopoietic protein 1
Approved Symbol:
NCKAP1L
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00781 Entrez Gene ID: 3071 OMIM ID: 141180 Swissprot Accession: P55160;