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Description for Protein ANXA3

annexin A3
6 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 7/1)
(alpha granules: 1; membrane: 1; microparticles: 1; platelet: 5; undefined: 1)
Summary:
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • ANX: Annexin repeats
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Annexin A3; ANX3; Lipocortin III; Placental anticoagulant protein III; PAP III; 35-alpha calcimedin; Inositol 1,2-cyclic phosphate 2-phosphohydrolase; EC 3.1.4.36
    Approved Symbol:
    ANXA3
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Ethanolamine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00111 Entrez Gene ID: 306 OMIM ID: 106490 Swissprot Accession: P12429;