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Description for Protein HAGH

hydroxyacylglutathione hydrolase
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(secretome: 2; undefined: 1)
Summary:
The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
3.1.2.6
KEGG - Orthology:
K01069
KEGG - Pathway(s):
hsa00620
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
GLO2; Glx II; Glyoxalase II; EC 3.1.2.6; Hydroxyacyl glutathione hydrolase isoform 2; Hydroxyacyl glutathione hydrolase isoform 1
Approved Symbol:
HAGH
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 6
Human (de-) phosphorylation sites: 6; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Acetate Ion(db);
  • Cacodylate Ion(db);
  • Glutathione(db);
  • S-(N-Hydroxy-N-Bromophenylcarbamoyl)Glutathione(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00731 Entrez Gene ID: 3029 OMIM ID: 138760 Swissprot Accession: Q16775;