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Description for Protein SLC40A1

solute carrier family 40 (iron-regulated transporter), member 1
2 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(membrane: 1; platelet: 1)
Summary:
The protein encoded by this gene is a cell membrane protein that may be involved in iron export from duodenal epithelial cells. Defects in this gene are a cause of hemochromatosis type 4 (HFE4). [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Solute carrier family 11, member 3; SLC11A3; FPN1; Iron regulated transporter 1; IREG1; MTP1
    Approved Symbol:
    SLC40A1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Hemochromatosis, type 4(Pd)
    		• Predicted Transmembrane Domains:
    05229_1(10)
    Additional Identifiers:

    HPRD: 05229 Entrez Gene ID: 30061 OMIM ID: 604653 Swissprot Accession: Q6FI62; Q9NP59;