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Description for Protein ACAA1

acetyl-CoA acyltransferase 1
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(membrane: 1)
Summary:
This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.3.1.16
    KEGG - Orthology:
    K07513
    KEGG - Pathway(s):
    hsa00071; hsa00280; hsa01040; hsa01100; hsa03320; hsa04146
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Acetyl coenzyme A acyltransferase (peroxisomal) 3 oxoacyl-coenzyme A; Peroxisomal 3 oxoacyl coenzyme A thiolase; 3 ketoacyl CoA thiolase, peroxisomal; Acetyl CoA acyltransferase; Beta ketothiolase; PTHIO; ACAA; THIO
    Approved Symbol:
    ACAA1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • 2-Methyl-2,4-Pentanediol(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 06815 Entrez Gene ID: 30 OMIM ID: 604054 Swissprot Accession: P09110; Q96CA6;