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Description for Protein CNOT7

CCR4-NOT transcription complex, subunit 7
13 total interacting proteins; 8 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K12581
KEGG - Pathway(s):
hsa03018
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
CCR4 NOT transcription complex, subunit 7; BTG1 binding factor 1; CCR4 associated factor 1; CAF1; CCR4-NOT transcription complex, subunit 7 isoform 2; CCR4-NOT transcription complex, subunit 7 isoform 1
Approved Symbol:
CNOT7
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 05370 Entrez Gene ID: 29883 OMIM ID: 604913 Swissprot Accession: Q9UIV1; B3KN35;