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Description for Protein GTF2A1

general transcription factor IIA, 1, 19/37kDa
28 total interacting proteins; 10 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K03122
KEGG - Pathway(s):
hsa03022
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
TF2A1; General transcription factor 2A, alpha/beta subunits; Transcription initiation factor 2A alpha and beta chains; TF2A p35 and p19 subunits; TF2A 42; TF2AL; p55; TFIIA; General transcription factor IIA, 1 (37kD and 19kD subunits); TFIIA alpha, p55 isoform 1; General transcription factor IIA1; TFIIAL; TFIIA alpha, p55 isoform 2
Approved Symbol:
GTF2A1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 8
Human (de-) phosphorylation sites: 8; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02748 Entrez Gene ID: 2957 OMIM ID: 600520 Swissprot Accession: P52655;