Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein GSTZ1

glutathione transferase zeta 1
3 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
2.5.1.18; 5.2.1.2
KEGG - Orthology:
K00799
K01800
KEGG - Pathway(s):
hsa00350; hsa00480; hsa00980; hsa00982; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
MAAI; Glutathione S transferase Z1; MAI; GSTZ1-1; MGC2029; EC 5.2.1.2; EC 2.5.1.18; Glutathione transferase zeta 1 isoform 1; Glutathione transferase zeta 1 isoform 2; Glutathione transferase zeta 1 isoform 3
Approved Symbol:
GSTZ1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • 1,4-Dithiothreitol(db);
  • Beta-Mercaptoethanol(db);
  • Glutathione(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04785 Entrez Gene ID: 2954 OMIM ID: 603758 Swissprot Accession: O43708; A6NED0; A6NNB8;