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Description for Protein GNRH1

gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
2 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH), also known as gonadoliberin-1, and prolactin release-inhibiting factor, also known as GnRH-associated peptide 1. LHRH stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K05252
    KEGG - Pathway(s):
    hsa04080; hsa04912
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    GnRH associated peptide I; Gonadoliberin I; Progonadoliberin I; Prolactin release inhibiting factor; GRH; GNRH; Luteinizing hormone releasing hormone; LHRH; Luliberin I; Gonadorelin; Gonadotropin-releasing hormone 1 (luteinizing-releasing hormone); LNRH; Gonadotropin-releasing hormone 1 (lutienizing hormone-releasing hormone); Gonadotropin-releasing hormone 1; PIF
    Approved Symbol:
    GNRH1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 08860 Entrez Gene ID: 2796 OMIM ID: 152760 Swissprot Accession: P01148;