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Description for Protein GNG11

guanine nucleotide binding protein (G protein), gamma 11
4 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 3/1)
(membrane: 1; platelet: 3)
Summary:
This gene is a member of the guanine nucleotide-binding protein (G protein) gamma family and encodes a lipid-anchored, cell membrane protein. As a member of the heterotrimeric G protein complex, this protein plays a role in this transmembrane signaling system. This protein is also subject to carboxyl-terminal processing. Decreased expression of this gene is associated with splenic marginal zone lymphomas. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K04546
    KEGG - Pathway(s):
    hsa04062
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Guanine nucleotide binding protein 11; Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma 11 subunit; Guanine nucleotide binding protein (G protein), gamma 11
    Approved Symbol:
    GNG11
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 11979 Entrez Gene ID: 2791 OMIM ID: 604390 Swissprot Accession: P61952; Q53Y01;