Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein GNAI2

guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
49 total interacting proteins; 18 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 8/2)
(membrane: 3; microparticles: 1; platelet: 10; secretome: 2; undefined: 1)
Summary:
The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins). The encoded protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only two are known so far. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K04630
KEGG - Pathway(s):
hsa04062; hsa04360; hsa04530; hsa04540; hsa04670; hsa04730; hsa04914; hsa04916; hsa05142
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
G protein, alpha inhibiting 2B; GNAI2B; Guanine nucleotide binding protein, alpha inhibiting activity polypeptide 2; Guanine nucleotide binding protein G (i) , alpha 2 subunit; Gi2-alpha
Approved Symbol:
GNAI2
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 6
Human (de-) phosphorylation sites: 6; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

  • Adrenal cortical tumor(Pd);
  • Pituitary adenoma, ACTH-secreting(Pd);
  • Ventricular tachycardia, idiopathic(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00764 Entrez Gene ID: 2771 OMIM ID: 139360 Swissprot Accession: P04899; B3KX51; B4DYA0;