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Description for Protein GLUD2

glutamate dehydrogenase 2
2 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 1)
Summary:
The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless. (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
1.4.1.3
KEGG - Orthology:
K00261
KEGG - Pathway(s):
hsa00250; hsa00330; hsa00471; hsa00910; hsa01100; hsa04964
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Glutamate dehydrogenase 2, mitochondrial; GLUDP1
Approved Symbol:
GLUD2
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 3
Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • L-Glutamic Acid(db);
  • NADH(db);
  • Nicotinamide-Adenine-Dinucleotide(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02143 Entrez Gene ID: 2747 OMIM ID: 300144 Swissprot Accession: P49448;