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Description for Protein MAT2B

methionine adenosyltransferase II, beta
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/0)
(platelet: 3; secretome: 2)
Summary:
The protein encoded by this gene belongs to the methionine adenosyltransferase (MAT) family. MAT catalyzes the biosynthesis of S-adenosylmethionine from methionine and ATP. This protein is the regulatory beta subunit of MAT. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
2.5.1.6
KEGG - Orthology:
K00789
KEGG - Pathway(s):
hsa00270; hsa00450; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
MAT2 beta; TGR; MAT-II; MGC12237; MATIIbeta; Nbla02999; dTDP-4-keto-6-deoxy-D-glucose 4-reductase; Beta regulatory subunit of methionine adenosyltransferase; Methionine adenosyltransferase II, beta isoform 1; Methionine adenosyltransferase II, beta isoform 2
Approved Symbol:
MAT2B
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 2
Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • L-Methionine(db);
  • S-Adenosylmethionine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 05701 Entrez Gene ID: 27430 OMIM ID: 605527 Swissprot Accession: Q9NZL9;