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Description for Protein PRPF19

PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
4 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
PSO4 is the human homolog of yeast Pso4, a gene essential for cell survival and DNA repair (Beck et al., 2008 [PubMed 18263876]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • UBOX: Modified RING finger domain
  • WD40: WD40 repeats
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    6.3.2.19
    KEGG - Orthology:
    K10599
    KEGG - Pathway(s):
    hsa03040; hsa04120
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    PSO4; NMP200; Nuclear matrix protein NMP200 related to splicing factor PRP19
    Approved Symbol:
    PRPF19
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 7
    Human (de-) phosphorylation sites: 7; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 12214 Entrez Gene ID: 27339 OMIM ID: 608330 Swissprot Accession: Q9UMS4;