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Description for Protein AMPD2

adenosine monophosphate deaminase 2
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 5/2)
(microparticles: 1; phosphoproteome: 1; platelet: 8; secretome: 2; undefined: 1)
Summary:
Adenosine monophosphate deaminase-2 (EC 3.5.4.6) catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.5.4.6
    KEGG - Orthology:
    K01490
    KEGG - Pathway(s):
    hsa00230; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Adenosine monophosphate deaminase 2 isoform L isoform 2; Adenosine monophosphate deaminase 2 isoform L isoform 3; AMP deaminase 2; AMP deaminase isoform L; EC 3.5.4.6; Adenosine monophosphate deaminase 2 isoform L isoform 1
    Approved Symbol:
    AMPD2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 45
    Human (de-) phosphorylation sites: 45; Platelet phosphorylation sites: 3
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 11808 Entrez Gene ID: 271 OMIM ID: 102771 Swissprot Accession: Q01433;