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Description for Protein ACAD8

acyl-CoA dehydrogenase family, member 8
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(secretome: 3)
Summary:
This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency. (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
1.3.99.-
KEGG - Orthology:
K11538
KEGG - Pathway(s):
hsa00280; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Acyl-Coenzyme A dehydrogenase family, member 8; Isobutyryl-CoA dehydrogenase; Activator-recruited cofactor 42 kDa component; ARC42; Acyl-CoA dehydrogenase family member 8, mitochondrial
Approved Symbol:
ACAD8
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Flavin-Adenine Dinucleotide(db);
  • Methacrylyl-Coenzyme A(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 11985 Entrez Gene ID: 27034 OMIM ID: 604773 Swissprot Accession: Q9UKU7; Q6ZWP6;