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Description for Protein GFPT1

glutamine--fructose-6-phosphate transaminase 1
6 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
2.6.1.16
KEGG - Orthology:
K00820
KEGG - Pathway(s):
hsa00250; hsa00520; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
GFAT1; GFPT1L; Hexosephosphate aminotransferase 1; D-Fructose-6-phosphate amidotransferase 1; Glucosamine-fructose-6-phosphate amidotransferase 1; EC 2.6.1.16
Approved Symbol:
GFPT1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 9
Human (de-) phosphorylation sites: 9; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00702 Entrez Gene ID: 2673 OMIM ID: 138292 Swissprot Accession: Q06210;