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Description for Protein NR6A1

nuclear receptor subfamily 6, group A, member 1
4 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. The gene expresses at least alternatively spliced transcript variants. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • HOLI: Ligand binding domain of hormone receptors
  • ZnF_C4: c4 zinc finger in nuclear hormone receptors
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K08561
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    RTR; GCNF; NR61; GCNF1; Retinoid receptor related testis specific receptor; Orphan nuclear receptor NR6A1; Germ cell nuclear factor; Nuclear receptor subfamily 6, group A, member 1 isoform 1; Nuclear receptor subfamily 6, group A, member 1 isoform 2; Nuclear receptor subfamily 6, group A, member 1 isoform 3
    Approved Symbol:
    NR6A1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 3
    Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04147 Entrez Gene ID: 2649 OMIM ID: 602778 Swissprot Accession: Q15406;