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Description for Protein CABYR

calcium binding tyrosine-(Y)-phosphorylation regulated
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation. A pseudogene on chromosome 3 has been identified for this gene. Transcript variants of this gene encode multiple protein isoforms. An additional transcript and isoform has not been fully characterized. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
None Available
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
Calcium-binding protein 86; Calcium-binding tyrosine phosphorylation-regulated protein isoform c; Calcium binding tyrosine phosphorylation regulated protein isoform b; Calcium binding tyrosine phosphorylation regulated protein isoform c; Calcium binding tyrosine phosphorylation regulated protein isoform d; Calcium binding tyrosine phosphorylation regulated protein isoform e; FSP2; CBP86; MGC9117; Fibrousheathin II; Calcium binding tyrosine phosphorylation regulated protein; Calcium binding tyrosine phosphorylation regulated protein isoform a
Approved Symbol:
CABYR
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 26
Human (de-) phosphorylation sites: 26; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 6 : 0
  • Isoform 5 : 0
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 10806 Entrez Gene ID: 26256 OMIM ID: 612135 Swissprot Accession: O75952;