Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein GATA3

GATA binding protein 3
17 total interacting proteins; 5 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • ZNF_GATA: zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K09182
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Hypothetical protein MGC5445; HDR; GATA binding protein 3 isoform 2; GATA binding protein 3 isoform 1; Hypothetical protein MGC2346; Hypothetical protein MGC5199; Enhancer binding protein GATA3
    Approved Symbol:
    GATA3
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 8
    Human (de-) phosphorylation sites: 8; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Hypoparathyroidism, sensorineural deafness, and renal disease(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00572 Entrez Gene ID: 2625 OMIM ID: 131320 Swissprot Accession: P23771;