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Description for Protein B3GAT3

beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/0)
(membrane: 1; platelet: 1)
Summary:
The protein encoded by this gene is a member of the glucuronyltransferase gene family, enzymes that exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product catalyzes the formation of the glycosaminoglycan-protein linkage by way of a glucuronyl transfer reaction in the final step of the biosynthesis of the linkage region of proteoglycans. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.4.1.135
    KEGG - Orthology:
    K10158
    KEGG - Pathway(s):
    hsa00532; hsa00534; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Glucuronosyltransferase-I; GLCATI; Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3; UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase; GlcUAT-I
    Approved Symbol:
    B3GAT3
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Udp-Glucuronic Acid(db);
  • Uridine-5'-Diphosphate(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 07564 Entrez Gene ID: 26229 OMIM ID: 606374 Swissprot Accession: O94766;