Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein ABHD12

abhydrolase domain containing 12
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(membrane: 1)
Summary:
The endocannabinoid lipid transmitter 2-arachidonoyl glycerol (2-AG) acts on cannabinoid receptors CB1 (CNR1; MIM 114610) and CB2 (CNR2; MIM 605051) and functions in synaptic plasticity and neuroinflammation. ABHD12 inactivates 2-AG by converting it into the metabolites arachidonate and glycerol (Fiskerstrand et al., 2010 [PubMed 20797687]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.1.1.23
    KEGG - Orthology:
    K13704
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    DKFZP434P106; Chromosome 20 open reading frame 22; Abhydrolase domain containing 12 isoform a; Abhydrolase domain containing 12 isoform b; C20orf22
    Approved Symbol:
    ABHD12
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 1
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 07094 Entrez Gene ID: 26090 OMIM ID: - Swissprot Accession: Q8N2K0;