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Description for Protein DNM3

dynamin 3
3 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(platelet: 7)
Summary:
Members of the dynamin family, such as DNM3, possess mechanochemical properties involved in actin-membrane processes, predominantly in membrane budding (Orth and McNiven, 2003 [PubMed 12517701]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • PH: Pleckstrin homology domain.
  • DYNC: Dynamin, GTPase
  • GED: Dynamin GTPase effector domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.6.5.5
    KEGG - Orthology:
    K01528
    KEGG - Pathway(s):
    hsa04144; hsa04666; hsa05100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    EC 3.6.5.5; Testicular dynamin; T-dynamin; Dyna III; KIAA0820; Dynamin family member
    Approved Symbol:
    DNM3
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 4
    Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 13241 Entrez Gene ID: 26052 OMIM ID: 611445 Swissprot Accession: Q9UQ16;