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Description for Protein L3MBTL1

l(3)mbt-like 1 (Drosophila)
11 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene represents a polycomb group gene. The encoded protein functions to regulate gene activity, likely via chromatin modification. The encoded protein may also be necessary for mitosis. Alternatively spliced transcript variants encoding different isoforms have been identified. (PubMed Links)
Domains and Motifs:
  • MBT: Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
  • ZnF_C2HC: zinc finger
  • NLS: Nuclear localization signal
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Lethal (3) malignant brain tumor l(3); L3MBT-LIKE; L(3)mbt protein homolog; L(3)mbt like isoform I; L(3)mbt like isoform II; L3MBTL1; KIAA0681; H-l(3)mbt protein; H-L(3)MBT
    Approved Symbol:
    L3MBTL1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • 2-(N-Morpholino)-Ethanesulfonic Acid(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 16387 Entrez Gene ID: 26013 OMIM ID: 608802 Swissprot Accession: Q9Y468; Q6ZWF5;