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Description for Protein LMOD1

leiomodin 1 (smooth muscle)
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • WH2: Wiskott Aldrich syndrome homology region 2
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    1D; SM-Lmod; SMLMOD; Leiomodin, muscle form; 64 kDa autoantigen D1; 64 kDa autoantigen 1D; 64 kDa autoantigen 1D3; Smooth muscle leiomodin; Hashimoto thyroiditis autoantigen, 64-KD D1; Thyroid and eye muscle autoantigen, 64-KD; Thyroid and eye muscle autoantigen D1(64kD); Thyroid-associated ophthalmopathy autoantigen; Thyroid associated ophthalmopathy autoantigen, 64-KD
    Approved Symbol:
    LMOD1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04093 Entrez Gene ID: 25802 OMIM ID: 602715 Swissprot Accession: P29536; B1APV6;