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Description for Protein SHPRH

SNF2 histone linker PHD RING helicase
6 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006 [PubMed 17108083]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • RING: Ring finger
  • HELIC: helicase superfamily c-terminal domain
  • NLS: Nuclear localization signal
  • DEXDc: DEAD-like helicases superfamily
  • H15: Domain in histone families 1 and 5
  • PHD: PHD zinc finger
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    SNF2 histone linker PHD RING helicase isoform 2; FLJ90837; KIAA2023; SNF2 histone linker PHD RING helicase isoform a
    Approved Symbol:
    SHPRH
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 7
    Human (de-) phosphorylation sites: 7; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 10476 Entrez Gene ID: 257218 OMIM ID: 608048 Swissprot Accession: Q149N8;