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Gene Ontology Information for protein PCSK9

Biological Process?

acylglycerol metabolic process (Total: 86, Platelet: 41) (Children)
alcohol metabolic process (Total: 500, Platelet: 224) (Children)
anatomical structure development (Total: 3019, Platelet: 932) (Children)
apoptosis (Total: 1236, Platelet: 480) (Children)
biological regulation (Total: 7303, Platelet: 2182) (Children)
biological_process (Total: 14352, Platelet: 4135) (Children)
catabolic process (Total: 1361, Platelet: 579) (Children)
cell communication (Total: 1626, Platelet: 498) (Children)
cell death (Total: 1357, Platelet: 533) (Children)
cell differentiation (Total: 2052, Platelet: 605) (Children)
cellular catabolic process (Total: 1083, Platelet: 471) (Children)
cellular component organization (Total: 3404, Platelet: 1223) (Children)
cellular component organization or biogenesis (Total: 3514, Platelet: 1239) (Children)
cellular developmental process (Total: 2095, Platelet: 620) (Children)
cellular lipid metabolic process (Total: 672, Platelet: 258) (Children)
cellular localization (Total: 1392, Platelet: 635) (Children)
cellular macromolecule catabolic process (Total: 501, Platelet: 210) (Children)
cellular macromolecule metabolic process (Total: 5820, Platelet: 1619) (Children)
cellular membrane organization (Total: 471, Platelet: 252) (Children)
cellular metabolic process (Total: 7674, Platelet: 2355) (Children)
cellular process (Total: 11864, Platelet: 3614) (Children)
cellular protein catabolic process (Total: 325, Platelet: 149) (Children)
cellular protein metabolic process (Total: 2583, Platelet: 1069) (Children)
cellular response to chemical stimulus (Total: 668, Platelet: 263) (Children)
cellular response to endogenous stimulus (Total: 293, Platelet: 134) (Children)
cellular response to external stimulus (Total: 106, Platelet: 32) (Children)
cellular response to extracellular stimulus (Total: 105, Platelet: 31) (Children)
cellular response to hormone stimulus (Total: 278, Platelet: 132) (Children)
cellular response to insulin stimulus (Total: 189, Platelet: 95) (Children)
cellular response to nutrient levels (Total: 83, Platelet: 24) (Children)
cellular response to organic substance (Total: 378, Platelet: 161) (Children)
cellular response to peptide hormone stimulus (Total: 200, Platelet: 100) (Children)
cellular response to starvation (Total: 46, Platelet: 17) (Children)
cellular response to stimulus (Total: 1418, Platelet: 490) (Children)
cellular response to stress (Total: 818, Platelet: 269) (Children)
chemical homeostasis (Total: 582, Platelet: 200) (Children)
cholesterol homeostasis (Total: 45, Platelet: 16) (Children)
cholesterol metabolic process (Total: 101, Platelet: 39) (Children)
death (Total: 1360, Platelet: 535) (Children)
developmental process (Total: 3603, Platelet: 1072) (Children)
endocytosis (Total: 292, Platelet: 154) (Children)
establishment of localization (Total: 3080, Platelet: 1236) (Children)
establishment of localization in cell (Total: 1285, Platelet: 602) (Children)
gene expression (Total: 3814, Platelet: 856) (Children)
generation of neurons (Total: 816, Platelet: 280) (Children)
glycerol ether metabolic process (Total: 100, Platelet: 52) (Children)
glycerolipid metabolic process (Total: 206, Platelet: 92) (Children)
hepaticobiliary system development (Total: 68, Platelet: 16) (Children)
homeostatic process (Total: 897, Platelet: 322) (Children)
induction of apoptosis (Total: 363, Platelet: 148) (Children)
induction of programmed cell death (Total: 364, Platelet: 148) (Children)
intracellular transport (Total: 777, Platelet: 388) (Children)
kidney development (Total: 118, Platelet: 19) (Children)
lipid homeostasis (Total: 65, Platelet: 24) (Children)
lipid metabolic process (Total: 994, Platelet: 367) (Children)
lipoprotein metabolic process (Total: 102, Platelet: 30) (Children)
liver development (Total: 67, Platelet: 16) (Children)
localization (Total: 3594, Platelet: 1402) (Children)
low-density lipoprotein particle clearance (Total: 10, Platelet: 5) (Children)
low-density lipoprotein receptor catabolic process (Total: 4, Platelet: 2) (Children)
low-density lipoprotein receptor metabolic process (Total: 9, Platelet: 5) (Children)
lysosomal transport (Total: 28, Platelet: 13) (Children)
macromolecule catabolic process (Total: 628, Platelet: 266) (Children)
macromolecule metabolic process (Total: 6391, Platelet: 1787) (Children)
membrane invagination (Total: 292, Platelet: 154) (Children)
membrane organization (Total: 473, Platelet: 253) (Children)
metabolic process (Total: 8630, Platelet: 2635) (Children)
multicellular organismal development (Total: 3297, Platelet: 972) (Children)
multicellular organismal process (Total: 5009, Platelet: 1402) (Children)
negative regulation of biological process (Total: 2258, Platelet: 752) (Children)
negative regulation of catalytic activity (Total: 321, Platelet: 138) (Children)
negative regulation of cellular metabolic process (Total: 860, Platelet: 276) (Children)
negative regulation of cellular process (Total: 2091, Platelet: 689) (Children)
negative regulation of lipoprotein particle clearance (Total: 6, Platelet: 1) (Children)
negative regulation of low-density lipoprotein particle clearance (Total: 3, Platelet: 1) (Children)
negative regulation of macromolecule metabolic process (Total: 878, Platelet: 272) (Children)
negative regulation of metabolic process (Total: 940, Platelet: 296) (Children)
negative regulation of molecular function (Total: 408, Platelet: 172) (Children)
negative regulation of multicellular organismal process (Total: 197, Platelet: 78) (Children)
negative regulation of receptor recycling (Total: 2, Platelet: ) (Children)
negative regulation of signaling process (Total: 134, Platelet: 47) (Children)
nervous system development (Total: 1368, Platelet: 420) (Children)
neurogenesis (Total: 862, Platelet: 297) (Children)
neuron apoptosis (Total: 104, Platelet: 42) (Children)
neuron death (Total: 106, Platelet: 44) (Children)
neuron differentiation (Total: 762, Platelet: 263) (Children)
neutral lipid metabolic process (Total: 87, Platelet: 42) (Children)
organ development (Total: 1848, Platelet: 544) (Children)
organic ether metabolic process (Total: 102, Platelet: 52) (Children)
organophosphate metabolic process (Total: 217, Platelet: 83) (Children)
phospholipid metabolic process (Total: 205, Platelet: 76) (Children)
plasma lipoprotein particle clearance (Total: 23, Platelet: 8) (Children)
positive regulation of apoptosis (Total: 492, Platelet: 189) (Children)
positive regulation of biological process (Total: 2456, Platelet: 839) (Children)
positive regulation of cell death (Total: 500, Platelet: 192) (Children)
positive regulation of cellular component organization (Total: 254, Platelet: 107) (Children)
positive regulation of cellular metabolic process (Total: 1109, Platelet: 339) (Children)
positive regulation of cellular process (Total: 2218, Platelet: 743) (Children)
positive regulation of endocytosis (Total: 48, Platelet: 24) (Children)
positive regulation of macromolecule metabolic process (Total: 1073, Platelet: 316) (Children)
positive regulation of metabolic process (Total: 1159, Platelet: 355) (Children)
positive regulation of neuron apoptosis (Total: 21, Platelet: 11) (Children)
positive regulation of programmed cell death (Total: 495, Platelet: 191) (Children)
positive regulation of receptor internalization (Total: 8, Platelet: 3) (Children)
positive regulation of receptor-mediated endocytosis (Total: 19, Platelet: 8) (Children)
positive regulation of transport (Total: 298, Platelet: 127) (Children)
primary metabolic process (Total: 7785, Platelet: 2334) (Children)
programmed cell death (Total: 1243, Platelet: 484) (Children)
protein autoprocessing (Total: 7, Platelet: 3) (Children)
protein catabolic process (Total: 391, Platelet: 180) (Children)
protein maturation (Total: 91, Platelet: 37) (Children)
protein maturation by peptide bond cleavage (Total: 56, Platelet: 23) (Children)
protein metabolic process (Total: 3059, Platelet: 1206) (Children)
protein processing (Total: 81, Platelet: 31) (Children)
proteolysis (Total: 811, Platelet: 292) (Children)
receptor catabolic process (Total: 8, Platelet: 4) (Children)
receptor internalization (Total: 31, Platelet: 14) (Children)
receptor metabolic process (Total: 72, Platelet: 32) (Children)
receptor recycling (Total: 12, Platelet: 5) (Children)
receptor-mediated endocytosis (Total: 90, Platelet: 42) (Children)
regulation of apoptosis (Total: 971, Platelet: 391) (Children)
regulation of biological process (Total: 6792, Platelet: 2001) (Children)
regulation of biological quality (Total: 2091, Platelet: 821) (Children)
regulation of catabolic process (Total: 298, Platelet: 123) (Children)
regulation of catalytic activity (Total: 989, Platelet: 393) (Children)
regulation of cell death (Total: 986, Platelet: 397) (Children)
regulation of cellular catabolic process (Total: 258, Platelet: 107) (Children)
regulation of cellular component organization (Total: 722, Platelet: 283) (Children)
regulation of cellular metabolic process (Total: 3844, Platelet: 947) (Children)
regulation of cellular process (Total: 6378, Platelet: 1857) (Children)
regulation of cellular protein metabolic process (Total: 611, Platelet: 284) (Children)
regulation of endocytosis (Total: 84, Platelet: 45) (Children)
regulation of lipoprotein particle clearance (Total: 8, Platelet: 1) (Children)
regulation of localization (Total: 842, Platelet: 338) (Children)
regulation of low-density lipoprotein particle clearance (Total: 3, Platelet: 1) (Children)
regulation of low-density lipoprotein receptor catabolic process (Total: 4, Platelet: 2) (Children)
regulation of macromolecule metabolic process (Total: 3469, Platelet: 808) (Children)
regulation of metabolic process (Total: 4150, Platelet: 1057) (Children)
regulation of molecular function (Total: 1198, Platelet: 458) (Children)
regulation of multicellular organismal process (Total: 1159, Platelet: 364) (Children)
regulation of neuron apoptosis (Total: 93, Platelet: 37) (Children)
regulation of primary metabolic process (Total: 3643, Platelet: 875) (Children)
regulation of programmed cell death (Total: 978, Platelet: 395) (Children)
regulation of protein catabolic process (Total: 91, Platelet: 43) (Children)
regulation of protein metabolic process (Total: 681, Platelet: 315) (Children)
regulation of receptor activity (Total: 21, Platelet: 12) (Children)
regulation of receptor internalization (Total: 10, Platelet: 3) (Children)
regulation of receptor recycling (Total: 10, Platelet: 5) (Children)
regulation of receptor-mediated endocytosis (Total: 29, Platelet: 14) (Children)
regulation of signal transduction (Total: 906, Platelet: 338) (Children)
regulation of signaling process (Total: 911, Platelet: 342) (Children)
regulation of transport (Total: 622, Platelet: 257) (Children)
regulation of vesicle-mediated transport (Total: 134, Platelet: 74) (Children)
renal system development (Total: 122, Platelet: 20) (Children)
response to chemical stimulus (Total: 1973, Platelet: 760) (Children)
response to endogenous stimulus (Total: 611, Platelet: 251) (Children)
response to external stimulus (Total: 989, Platelet: 370) (Children)
response to extracellular stimulus (Total: 274, Platelet: 92) (Children)
response to hormone stimulus (Total: 550, Platelet: 232) (Children)
response to insulin stimulus (Total: 231, Platelet: 109) (Children)
response to nutrient levels (Total: 251, Platelet: 83) (Children)
response to organic substance (Total: 1006, Platelet: 406) (Children)
response to peptide hormone stimulus (Total: 298, Platelet: 132) (Children)
response to starvation (Total: 60, Platelet: 19) (Children)
response to stimulus (Total: 4334, Platelet: 1386) (Children)
response to stress (Total: 2244, Platelet: 861) (Children)
signal transduction (Total: 2360, Platelet: 866) (Children)
signal transmission (Total: 2761, Platelet: 992) (Children)
signaling (Total: 3833, Platelet: 1267) (Children)
signaling process (Total: 2766, Platelet: 995) (Children)
small molecule metabolic process (Total: 1861, Platelet: 788) (Children)
steroid metabolic process (Total: 258, Platelet: 86) (Children)
sterol homeostasis (Total: 45, Platelet: 16) (Children)
sterol metabolic process (Total: 108, Platelet: 44) (Children)
system development (Total: 2744, Platelet: 845) (Children)
transport (Total: 3041, Platelet: 1226) (Children)
triglyceride metabolic process (Total: 80, Platelet: 40) (Children)
urogenital system development (Total: 159, Platelet: 35) (Children)
vacuolar transport (Total: 32, Platelet: 14) (Children)
vesicle-mediated transport (Total: 765, Platelet: 443) (Children)


Molecular Function?

apolipoprotein receptor binding (Total: 3, Platelet:2) (Children)
binding (Total: 12782, Platelet: 3830) (Children)
catalytic activity (Total: 5218, Platelet: 1872) (Children)
endopeptidase activity (Total: 368, Platelet:112) (Children)
hydrolase activity (Total: 2290, Platelet: 808) (Children)
identical protein binding (Total: 707, Platelet: 273) (Children)
lipoprotein receptor binding (Total: 17, Platelet:11) (Children)
low-density lipoprotein receptor binding (Total: 13, Platelet:7) (Children)
molecular_function (Total: 15594, Platelet: 4389) (Children)
peptidase activity (Total: 564, Platelet: 170) (Children)
peptidase activity, acting on L-amino acid peptides (Total: 545, Platelet: 160) (Children)
protein binding (Total: 8959, Platelet: 2987) (Children)
receptor binding (Total: 964, Platelet: 307) (Children)
serine hydrolase activity (Total: 172, Platelet:46) (Children)
serine-type endopeptidase activity (Total: 148, Platelet:36) (Children)
serine-type peptidase activity (Total: 169, Platelet:45) (Children)
very-low-density lipoprotein receptor binding (Total: 3, Platelet:1) (Children)


Cellular Component?

cell (Total: 14910, Platelet: 4246) (Children)
cell part (Total: 14909, Platelet: 4246) (Children)
cell periphery (Total: 3988, Platelet: 1164) (Children)
cell surface (Total: 355, Platelet: 140) (Children)
cellular_component (Total: 16194, Platelet: 4465) (Children)
cytoplasm (Total: 7967, Platelet: 3091) (Children)
cytoplasmic part (Total: 5701, Platelet: 2428) (Children)
endoplasmic reticulum (Total: 1059, Platelet: 449) (Children)
endosome (Total: 413, Platelet: 204) (Children)
external side of plasma membrane (Total: 142, Platelet: 57) (Children)
extracellular region (Total: 2039, Platelet: 482) (Children)
extracellular region part (Total: 1025, Platelet: 270) (Children)
extracellular space (Total: 788, Platelet: 217) (Children)
extrinsic to external side of plasma membrane (Total: 6, Platelet: 4) (Children)
extrinsic to membrane (Total: 90, Platelet: 40) (Children)
extrinsic to plasma membrane (Total: 55, Platelet: 29) (Children)
intracellular (Total: 11408, Platelet: 3621) (Children)
intracellular membrane-bounded organelle (Total: 8536, Platelet: 2625) (Children)
intracellular organelle (Total: 9480, Platelet: 2972) (Children)
intracellular part (Total: 11122, Platelet: 3557) (Children)
late endosome (Total: 115, Platelet: 59) (Children)
lysosome (Total: 261, Platelet: 109) (Children)
lytic vacuole (Total: 261, Platelet: 109) (Children)
membrane (Total: 7288, Platelet: 2217) (Children)
membrane part (Total: 6024, Platelet: 1655) (Children)
membrane-bounded organelle (Total: 8543, Platelet: 2629) (Children)
organelle (Total: 9495, Platelet: 2974) (Children)
perinuclear region of cytoplasm (Total: 346, Platelet: 158) (Children)
plasma membrane (Total: 3926, Platelet: 1133) (Children)
plasma membrane part (Total: 2055, Platelet: 621) (Children)
rough endoplasmic reticulum (Total: 36, Platelet: 19) (Children)
vacuole (Total: 309, Platelet: 130) (Children)