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Description for Protein GABPB1

GA binding protein transcription factor, beta subunit 1
12 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • ANK: ankyrin repeats
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K09454
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    BABPB2; E4TF1B; GABPB1; NRF2B1; NRF2B2; Adenovirus E4 gene transcription factor 1, 47-KD subunit; E4TF1-47; E4TF1-53; Nuclear respiratory factor 2 beta subunit 1; Nuclear respiratory factor 2 beta subunit 2; Adenovirus E4 gene transcription factor 1, 53-KD subunit; GA binding protein transcription factor beta subunit 2, 47kD; Nuclear respiratory factor 2 subunit beta; GA binding protein transcription factor beta subunit 1,53kDa; E4TF1; GABPB; GABP-GAMMA; GA binding protein transcription factor, beta subunit 2; Transcription factor E4TF1-53; Transcription factor E4TF1-47; GABP-beta-2 subunit; GABP-beta-1 subunit; Nuclear respiratory factor 2; GA binding protein beta chain; GA binding protein transcription factor, beta subunit 2 isoform gamma 1; GA binding protein transcription factor, beta subunit 2 isoform beta 1; GA binding protein transcription factor, beta subunit 2 isoform beta 2; GA binding protein transcription factor, beta subunit 2 isoform gamma 2
    Approved Symbol:
    GABPB1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 5 : 0
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 15975 Entrez Gene ID: 2553 OMIM ID: 600610 Swissprot Accession: Q06547;