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Description for Protein ALPPL2

alkaline phosphatase, placental-like 2
2 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.1.3.1
    KEGG - Orthology:
    K01077
    KEGG - Pathway(s):
    hsa00790; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Alkaline phosphatase, germ cell; ALPG; GCAP; Alkaline phosphatase, testicular and thymus; Nagao isozyme; Alkaline phosphatase, placental like 2; PLAP like; ALPPL
    Approved Symbol:
    ALPPL2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Amifostine(db);
  • Levamisole(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01380 Entrez Gene ID: 251 OMIM ID: 171810 Swissprot Accession: P10696; P05187;