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Description for Protein KIF4A

kinesin family member 4A
5 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a member of the kinesin 4 subfamily of kinesin related proteins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X. (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • KISC: Kinesin motor, catalytic domain. ATPase.
  • NLS: Nuclear localization signal
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K10395
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Kinesin family member 4A; Chromokinesin; KIF4; KIF4G1; HSA271784
    Approved Symbol:
    KIF4A
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 42
    Human (de-) phosphorylation sites: 42; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 06606 Entrez Gene ID: 24137 OMIM ID: 300521 Swissprot Accession: O95239; Q59HG1;