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Description for Protein PISD

phosphatidylserine decarboxylase
2 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Phosphatidylserine decarboxylases (PSDs; EC 4.1.1.65) catalyze the formation of phosphatidylethanolamine (PE) by decarboxylation of phosphatidylserine (PS). Type I PSDs, such as PISD, are targeted to the inner mitochondrial membrane by an N-terminal targeting sequence. PISD also contains a conserved LGST motif that functions as an autocatalytic cleavage site where the proenzyme is split into mature alpha and beta subunits (Schuiki and Daum, 2009 [PubMed 19165886]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
4.1.1.65
KEGG - Orthology:
K01613
KEGG - Pathway(s):
hsa00564; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
PSSC; DJ858B16; dJ858B16.2; DKFZP566G2246; Phosphatidylserine decarboxylase proenzyme; Phosphatidylserine decarboxylase alpha chain; Phosphatidylserine decarboxylase beta chain; EC 4.1.1.65
Approved Symbol:
PISD
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Phosphatidylserine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 17854 Entrez Gene ID: 23761 OMIM ID: 612770 Swissprot Accession: B1AKM7; Q9UG56;