Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein SLC7A11

solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
2 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
SLC7A11 is a member of a heteromeric Na(+)-independent anionic amino acid transport system highly specific for cystine and glutamate. In this system, designated system Xc(-), the anionic form of cystine is transported in exchange for glutamate.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K13869
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    XCT; CCBR1; Cystine/glutamate transporter; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1
    Approved Symbol:
    SLC7A11
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • L-Cystine(db);
  • L-Glutamic Acid(db);
  • Riluzole(db);
  • Sulfasalazine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
    09720_1(12)
    Additional Identifiers:

    HPRD: 09720 Entrez Gene ID: 23657 OMIM ID: 607933 Swissprot Accession: Q9UPY5; A8K2U4;