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Description for Protein PIK3R5

phosphoinositide-3-kinase, regulatory subunit 5
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Receptor-regulated class I phosphoinositide 3-kinases (PI3Ks) phosphorylate the membrane lipid phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to PtdIns(3,4,5)P3, which in turn recruits and activates cytosolic effectors involved in proliferation, survival, or chemotaxis. PIK3R5 is a PI3K regulatory subunit (Brock et al., 2003 [PubMed 12507995]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K02649
KEGG - Pathway(s):
hsa04012; hsa04062; hsa04070; hsa04150; hsa04210; hsa04370; hsa04510; hsa04620; hsa04630; hsa04650; hsa04660; hsa04662; hsa04664; hsa04666; hsa04670; hsa04722; hsa04810; hsa04910; hsa04914; hsa04930; hsa04960; hsa05100; hsa05142; hsa05200; hsa05210; hsa05211; hsa05212; hsa05213; hsa05214; hsa05215; hsa05218; hsa05220; hsa05221; hsa05222; hsa05223
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
FOAP-2; P101-PI3K; F730038I15Rik; Phosphoinositide-3-kinase, regulatory subunit, polypeptide p101
Approved Symbol:
PIK3R5
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 4
Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 11433 Entrez Gene ID: 23533 OMIM ID: 611317 Swissprot Accession: Q8WYR1;