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Description for Protein HARS2

histidyl-tRNA synthetase 2, mitochondrial (putative)
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(platelet: 10)
Summary:
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes share a bidirectional promoter. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available

Gene Ontology:
Gene Ontology Annotations

KEGG - Enzyme ID(s):
6.1.1.21
KEGG - Orthology:
K01892
KEGG - Pathway(s):
hsa00970
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
HARS related gene; HisRS; HARSR; HO3
Approved Symbol:
HARS2
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 1
Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites

Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available


Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 02871 Entrez Gene ID: 23438 OMIM ID: 600783 Swissprot Accession: P49590