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Description for Protein SRGAP2

SLIT-ROBO Rho GTPase activating protein 2
10 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
(PubMed Links)
Domains and Motifs:
  • FCH: Fes/CIP4 homology domain
  • CC: Coiled Coil
  • RHOGAP: GTPase-activator protein for Rho-like GTPases
  • SH3: Src homology 3 domains
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K07526
    KEGG - Pathway(s):
    hsa04360
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    FNBP2; srGAP3; KIAA0456; Formin binding protein 2; SLIT-ROBO Rho GTPase activating protein 2 isoform b; SLIT-ROBO Rho GTPase activating protein 2 isoform a
    Approved Symbol:
    SRGAP2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 30
    Human (de-) phosphorylation sites: 30; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 18520 Entrez Gene ID: 23380 OMIM ID: 606524 Swissprot Accession: O75044; B7ZM87; A2RUF3;