Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein SYNE2

spectrin repeat containing, nuclear envelope 2
2 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • NLS: Nuclear localization signal
  • SPECTRIN: Spectrin repeat
  • CH: Calponin homology domain
  • LZ: Leucine Zipper
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Synaptic nuclear envelope protein 2; Nuclear envelope spectrin repeat protein 2; Nucleus and actin connecting element; Nuance; KIAA1011; NUA; FLJ46790; Synaptic nuclei expressed gene 2; Spectrin repeat containing, nuclear envelope 2 isoform a; Spectrin repeat containing, nuclear envelope 2 isoform d; Spectrin repeat containing, nuclear envelope 2 isoform b; Spectrin repeat containing, nuclear envelope 2 isoform e
    Approved Symbol:
    SYNE2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 38
    Human (de-) phosphorylation sites: 38; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 5 : 0
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09763 Entrez Gene ID: 23224 OMIM ID: 608442 Swissprot Accession: Q8WXH0; Q6MZP0;