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Description for Protein ATP11B

ATPase, class VI, type 11B
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(membrane: 1)
Summary:
P-type ATPases, such as ATP11B, are phosphorylated in their intermediate state and drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily transports heavy metal ions, such as Cu(2+) or Cd(2+). Another subfamily transports non-heavy metal ions, such as H(+), Na(+), K(+), or Ca(+). A third subfamily transports amphipaths, such as phosphatidylserine.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.6.3.1
    KEGG - Orthology:
    K01530
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    ATPIF; ATPIR; KIAA0956; MGC46576; DKFZP434J238; DKFZP434N1615; ATPase class I type 11B; EC 3.6.3.1; Potential phospholipid-transporting ATPase IF; ATPase IR
    Approved Symbol:
    ATP11B
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 3
    Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 8
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 10432 Entrez Gene ID: 23200 OMIM ID: 605869 Swissprot Accession: Q9Y2G3;