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Description for Protein RAP1GAP2

RAP1 GTPase activating protein 2
3 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(platelet: 2; undefined: 1)
Summary:
This gene encodes a GTPase-activating protein that activates the small guanine-nucleotide-binding protein Rap1 in platelets. The protein interacts with synaptotagmin-like protein 1 and Rab27 and regulates secretion of dense granules from platelets at sites of endothelial damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
None Available
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
RAP1GA3; KIAA1039; Rap1 GTPase activating protein IIIa; Rap1 GTPase activating protein IIIb; GTPase activating RANGAP domain-like 4
Approved Symbol:
RAP1GAP2
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 19
Human (de-) phosphorylation sites: 19; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 17028 Entrez Gene ID: 23108 OMIM ID: - Swissprot Accession: Q684P5;