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Description for Protein KIF1B

kinesin family member 1B
14 total interacting proteins; 8 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a motor protein that transports mitochondria and synaptic vesicle precursors. Mutations in this gene cause Charcot-Marie-Tooth disease, type 2A1. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • PH: Pleckstrin homology domain.
  • KISC: Kinesin motor, catalytic domain. ATPase.
  • CC: Coiled Coil
  • FHA: Forkhead associated domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K10392
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Kinesin family member 1B isoform alpha; Klp; KIAA0591; KIAA1448; CMT2; CMT2A; CMT2A1; Kinesin family member 1B isoform b
    Approved Symbol:
    KIF1B
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 20
    Human (de-) phosphorylation sites: 20; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Charcot-Marie-tooth disease, axonal, type 2A1(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 05818 Entrez Gene ID: 23095 OMIM ID: 605995 Swissprot Accession: O60333;