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Description for Protein KDM1A

lysine (K)-specific demethylase 1A
25 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    1.-.-.-
    KEGG - Orthology:
    K11450
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    KIAA0601; Amine oxidase (flavin containing) domain 2; LSD1; BRAF35-HDAC complex protein BHC110; Lysine-specific histone demethylase 1; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; amine oxidase domain 2 isoform b; amine oxidase domain 2 isoform a
    Approved Symbol:
    KDM1A
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 17
    Human (de-) phosphorylation sites: 17; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09800 Entrez Gene ID: 23028 OMIM ID: 609132 Swissprot Accession: O60341;