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Description for Protein CD93

CD93 molecule
20 total interacting proteins; 11 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(membrane: 1; undefined: 1)
Summary:
The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • EGFL: EGF domain, unclasssified subfamily
  • LECTIN_C: C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
  • EGFCA: Calcium-binding EGF-like domain
  • TM: Transmembrane domain
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K06702
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Complement component 1, q subcomponent, receptor 1; C1QR; Collectin receptor; C1qRp; C1qR(p); C1q/MBL/SPA receptor; C1q receptor 1; CDw93; CD93; CD93 antigen
    Approved Symbol:
    CD93
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 00396 Entrez Gene ID: 22918 OMIM ID: 120577 Swissprot Accession: Q9NPY3;