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Description for Protein DHX30

DEAH (Asp-Glu-Ala-His) box polypeptide 30
12 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The encoded protein has 97% sequence identity with the mouse HELG protein. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • DEXDc: DEAD-like helicases superfamily
  • DSRM: Double-stranded RNA binding motif
  • HELIC: helicase superfamily c-terminal domain

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    3.6.1.-
    KEGG - Orthology:
    K13185
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    DDX30; DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2; DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1; DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 3; FLJ11214; KIAA0890; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 30; DEAD box polypeptide 30
    Approved Symbol:
    DHX30
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 18
    Human (de-) phosphorylation sites: 18; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 13142 Entrez Gene ID: 22907 OMIM ID: - Swissprot Accession: Q7L2E3