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Description for Protein SEC31A

SEC31 homolog A (S. cerevisiae)
2 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/1)
(platelet: 23)
Summary:
The protein encoded by this gene is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII , in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • WD40: WD40 repeats

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    DKFZp686N07171; MGC90305; Protein-transport protein SEC31; Sec31p homolog; ABP125; ABP130; SEC31A; HSPC275; HSPC334; KIAA0905; SEC31 homolog A isoform 4; SEC31 homolog A isoform 1; SEC31 homolog A isoform 3; SEC31 homolog A isoform 2; SEC31 homolog A
    Approved Symbol:
    SEC31A
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 32
    Human (de-) phosphorylation sites: 32; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 5 : 0
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 15314 Entrez Gene ID: 22872 OMIM ID: 610257 Swissprot Accession: O94979