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Description for Protein DLGAP4

discs, large (Drosophila) homolog-associated protein 4
15 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 7)
Summary:
The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
None Available
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
RP5-977B1.6; PSD-95/SAP90 binding protein 4; SAP90/PSD-95 associated protein 4; DAP-4; SAPAP4; DAP4; KIAA0964; Disks large-associated protein 4 isoform a; Disks large-associated protein 4 isoform b; Disks large-associated protein 4 isoform c
Approved Symbol:
DLGAP4
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 18
Human (de-) phosphorylation sites: 18; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 16826 Entrez Gene ID: 22839 OMIM ID: - Swissprot Accession: Q9Y2H0;