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Description for Protein RRAS2

related RAS viral (r-ras) oncogene homolog 2
27 total interacting proteins; 10 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/0)
(membrane: 1; platelet: 1)
Summary:
This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • RAS: Ras subfamily of RAS small GTPases
  • Small_GTPase: Small GTPase of the Ras superfamily
  • ill-defined subfamily
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K07830
    KEGG - Pathway(s):
    hsa04010; hsa04530; hsa04810
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Teratocarcinoma oncogene TC21; TC21; Ras related protein R Ras2
    Approved Symbol:
    RRAS2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 4
    Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Ovarian carcinoma(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02518 Entrez Gene ID: 22800 OMIM ID: 600098 Swissprot Accession: P62070; B7Z7H6;